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PF 562271

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10459
    PF-562271
    Maximum Cited Publications
    19 Publications Verification

    VS-6062

    		 FAK Pyk2 Cancer
    PF-562271 (VS-6062) is a potent, ATP-competitive and reversible FAK and Pyk2 kinase inhibitor with IC50s of 1.5 nM and 13 nM, respectively .
    <em>PF-562271</em>
  • HY-10458
    PF-562271 besylate
    Maximum Cited Publications
    19 Publications Verification

    VS-6062 besylate

    		 FAK Pyk2 Cancer
    PF-562271 (VS-6062) besylate is a potent ATP-competitive, reversible inhibitor of FAK and Pyk2 kinase, with an IC50 of 1.5 nM and 13 nM, respectively .
    <em>PF-562271</em> besylate
  • HY-139344
    FC-11

    		FAK PROTACs Cancer
    FC-11 is a PROTAC FAK degrader (DC90: 1 nM) . FC-11 contains CRBN ligand Pomalidomide (HY-10984), linker and FAK ligand PF562271 (HY-10459). FC-11 degrades FAK in various cells, with DC50s of 310 pM in TM3, 80 pM in PA1, 330 pM in MDA-MB-436, 370 pM in LNCaP, and 40 pM in Ramos cells .
    FC-11
  • HY-20403
    PF-562271 hydrochloride

    VS-6062(hydrochloride)

    		 FAK Pyk2 Cancer
    PF-562271 (VS-6062) hydrochloride is a potent, ATP-competitive and reversible FAK and Pyk2 kinase inhibitor with IC50s of 1.5 nM and 13 nM, respectively .
    <em>PF-562271</em> hydrochloride

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